南澳代写作业:药物的活性成分

2018-01-20 23:56

控释剂型的制定是为了使药物的活性成分在一段较长的时间内逐渐释放出来，大概是12到24小时。“这些制剂可以通过更一致地提供药物来提高治疗慢性疾病的有效性;减少副作用;更方便;而与直接释放药物相比，由于剂量计划的简化，病人的依从性更高。布洛芬是一种无色、透明的固体，它在水中有一个低可溶性的极限，但它在大多数有机溶剂中具有更好的溶解性。这项工作的主要目的是控制药物的释放，将其封装在诸如fattyacid (palmiticacid和pluronic F-127)等涂层材料中。布洛芬,利用冷冻干燥技术的封装技术布洛芬是封装在fattyacid和普朗尼克(F127),这些涂料的性质控制药物的释放,当涂层药物进入身体的涂层材料包围的药物控制释放药物”。通过溶解和紫外可见光谱学，测定了布洛芬胶囊的释放量。
南澳代写作业:药物的活性成分
The Controlled-release dosage forms are formulated to release the drug's active ingredient gradually and predictably over an extended period of time that is something like 12 to 24 hour period. “These formulations potentially provide for greater effectiveness in the treatment of chronic conditions through more consistent delivery of the medication; reduced side effects; greater convenience; and higher levels of patient compliance due to a simplified dosage schedule, compared with those of immediate-release drugs”. Ibuprofen is a colourless, crystalline solid which is having a low soluble limits in water but it is having a better solublity in most organic solvents. “The main aim of this work is control the release of drug by encapsulating it in to coating materials like fattyacids (palmiticacid and pluronic F-127). Encapsulating of ibuprofen by using freeze drying technique in this technique Ibuprofen is encapsulated in to the fattyacid and pluronic (F127), these coating materials have the property of controlling the release of drug when the coated drug is entered in to the body the coating materials which surrounded to the drug is control the release of drug”. The release of encapsulated ibuprofen is determined by Flow through dissolution and UV- visible spectroscopy.

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